Publication details
Krassowski T, Coughlan AY, Shen XX, Zhou X, Kominek J, Opulente DA, Riley R, Grigoriev IV, Maheshwari N, Shields DC, Kurtzman CP, Hittinger CT, Rokas A, Wolfe KH
Abstract: The genetic code used in nuclear genes is almost universal, but here we report that it changed three times in parallel during the evolution of budding yeasts. All three changes were reassignments of the codon CUG, which is translated as serine (in 2 yeast clades), alanine (1 clade), or the 'universal' leucine (2 clades). The newly discovered Ser2 clade is in the final stages of a genetic code transition. Most species in this clade have genes for both a novel tRNA(Ser)(CAG) and an ancestral tRNA(Leu)(CAG) to read CUG, but only tRNA(Ser)(CAG) is used in standard growth conditions. The coexistence of these alloacceptor tRNA genes indicates that the genetic code transition occurred via an ambiguous translation phase. We propose that the three parallel reassignments of CUG were not driven by natural selection in favor of their effects on the proteome, but by selection to eliminate the ancestral tRNA(Leu)(CAG).
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Peterozyma xylosa NRRL Y-12939
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[ Opisthokonta | Fungi | Dikarya | . . .
. . . | Saccharomycetales | Debaryomycetaceae | Peterozyma ]
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| Publication: |
Krassowski T, Coughlan AY, Shen XX et. al. 
( 2018)
Nat Commun 9, 1887.
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Nakazawaea wickerhamii NRRL Y-2563
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[ Opisthokonta | Fungi | Dikarya | . . .
. . . | Saccharomycetales | Pichiaceae | Nakazawaea ]
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| Publication: |
Krassowski T, Coughlan AY, Shen XX et. al.
( 2018)
Nat Commun 9, 1887.
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Saturnispora dispora NRRL Y-1447
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[ Opisthokonta | Fungi | Dikarya | . . .
. . . | Saccharomycetales | Pichiaceae | Saturnispora ]
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| Publication: |
Krassowski T, Coughlan AY, Shen XX et. al.
( 2018)
Nat Commun 9, 1887.
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Candida boidinii NRRL Y-2332
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[ Opisthokonta | Fungi | Dikarya | . . .
. . . | Pichiaceae | Ogataea | Ogataea/Candida clade ]
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| Publication: |
Krassowski T, Coughlan AY, Shen XX et. al.
( 2018)
Nat Commun 9, 1887.
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Saccharomycopsis capsularis NRRL Y-17639
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[ Opisthokonta | Fungi | Dikarya | . . .
. . . | Saccharomycetales | Saccharomycopsidaceae | Saccharomycopsis ]
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| Publication: |
Krassowski T, Coughlan AY, Shen XX et. al.
( 2018)
Nat Commun 9, 1887.
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Ambrosiozyma philentoma NRRL Y-7523
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[ Opisthokonta | Fungi | Dikarya | . . .
. . . | Saccharomycetales | Saccharomycetales incertae sedis | Ambrosiozyma ]
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| Publication: |
Krassowski T, Coughlan AY, Shen XX et. al.
( 2018)
Nat Commun 9, 1887.
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Citeromyces matritensis NRRL Y-2407
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[ Opisthokonta | Fungi | Dikarya | . . .
. . . | Saccharomycetales | Saccharomycetaceae | Citeromyces ]
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| Taxonomy: | Eukaryota | Opisthokonta | Fungi | Dikarya | Ascomycota | saccharomyceta | Saccharomycotina | Saccharomycetes | Saccharomycetales | Saccharomycetaceae | Citeromyces |
| Anamorph: | Candida globosa |
| Synonym: | Hansenula matritensis |
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Go to NCBI Taxonomy (36909) |
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Encyclopedia of life |
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Wikipedia |
| Publication: |
Krassowski T, Coughlan AY, Shen XX et. al.
( 2018)
Nat Commun 9, 1887.
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