Species

Acanthamoeba castellanii

[ Amoebozoa | Discosea | Longamoebia | . . .
. . . | Centramoebida | Acanthamoebidae | Acanthamoeba ]

Courtesy of Dr Steven Dobberstein

Taxonomy: Eukaryota | Amoebozoa | Discosea | Longamoebia | Centramoebida | Acanthamoebidae | Acanthamoeba Comment: Acanthamoeba castellanii is commonly isolated from terrestrial and aquatic environments. This organism forms a thick-walled cyst which is resistant to heat, dessication, and disinfectants. Acanthamoeba castellanii is an opportunistic pathogen that can cause a severe encephalitis in immunocompromised patients, and keratitis in contact lens wearers. Go to NCBI Taxonomy (5755) Encyclopedia of life Wikipedia Projects: Human Genome Sequencing Center at Baylor College of Medicine: Acanthamoeba castellani Neff International TSA Sequencing Consortium: Acanthamoeba castellanii TSA Sequencing Consortium National Center for Biotechnology Information: NCBI Protozoa genomes TBestDB - Taxonomically Broad EST Database: Acanthamoeba castellanii Publications: Martin-Navarro CM, Lorenzo-Morales J, Machin RP et. al. (2013) Inhibition of 3-Hydroxy-3-Methylglutaryl-Coenzyme A Reductase and Application of Statins as a Novel Effective Therapeutic Approach against Acanthamoeba Infections. Antimicrob Agents Chemother 57, 375-381. 10.1128/AAC.01426-12 Clarke M, Lohan AJ, Liu B et. al. (2013) Genome of Acanthamoeba castellanii highlights extensive lateral gene transfer and early evolution of tyrosine kinase signaling. Genome Biol 14, R11. 10.1186/gb-2013-14-2-r11 Leger MM, Gawryluk RM, Gray MW et. al. (2013) Evidence for a hydrogenosomal-type anaerobic ATP generation pathway in Acanthamoeba castellanii. PLoS One 8, e69532. 10.1371/journal.pone.0069532 Genome files Human Genome Sequencing Center at Baylor College of Medicine Type Version Date Compl Cov GC % Size (Mbp) Contigs CGR Illegal Chars N50 (kbp) Acc File Seq info Contigs v 1.0.0 2008-01-30 25 58.3 48.8 31091 - 4 - Supercontigs v 1.0.0 2008-01-30 25 58.3 47.0 18936 - 235 - National Center for Biotechnology Information Type Version Date Compl Cov GC % Size (Mbp) Contigs CGR Illegal Chars N50 (kbp) Acc File Seq info Contigs v 1.0.0 2011-03-10 30 58.4 46.4 2545 - 104 Contigs assembly 02 v 1.0.0 2012-10-24 58.4 39.4 3192 - 44 Contigs assembly 03 v 1.0.0 2014-11-06 - 58.9 113.8 221748 2 Supercontigs v 1.0.0 2011-03-10 30 58.5 43.5 210 - 602 Supercontigs assembly 02 v 1.0.0 2012-10-24 58.4 39.4 384 - 344 TSA v 1.0.0 2013-08-29 62.5 0.0 8 -