[ Opisthokonta | Metazoa | Eumetazoa | . . .
. . . | Sophophora | melanogaster group | melanogaster subgroup ]
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Taxonomy: | Eukaryota | Opisthokonta | Metazoa | Eumetazoa | Bilateria | Protostomia | Ecdysozoa | Panarthropoda | Arthropoda | Mandibulata | Pancrustacea | Hexapoda | Insecta | Dicondylia | Pterygota | Neoptera | Holometabola | Diptera | Brachycera | Muscomorpha | Eremoneura | Cyclorrhapha | Schizophora | Acalyptratae | Ephydroidea | Drosophilidae | Drosophilinae | Drosophilini | Drosophila | Sophophora | melanogaster group | melanogaster subgroup |
Comment: | The Release 1.0 D. simulans assembly represents a mosaic of several different D. simulans lines. The assembly process began with an ~4X WGS assembly of the the D. simulans w501 line. The w501 contigs were initially anchored, ordered and oriented by alignment with the D. melanogaster genome. The assembly was then examined for places where the w501 assembly suggested inversions with respect to the D. melanogaster assembly. One major inversion was found, confirming the already documented inversion found by Lemeunier and Ashburner (1976). Six other D. simulans lines (c167.4, md106ts, md199s, nc48s, sim4, and sim6) were assembled with ~1X coverage. Using the 4X WGS assembly of the simulans w501 genome as a scaffold, contigs and unplaced reads from the 1X assemblies of the other individual D. simulans lines were used to cover gaps in the w501 assembly where possible. Thus the resulting assembly is a mosaic containing the w501 contigs as the primary scaffolding, with contigs and unplaced reads from the other lines filling gaps in the w501 assembly. |
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Go to NCBI Taxonomy (7240) |
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Encyclopedia of life |
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Publication: |
Clark AG, Eisen MB, Smith DR et. al.
( 2007)
Nature 450, 203-218.
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Genome files
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